Poly(lactic-co-glycolic acid) Bone Scaffolds with Inverted Colloidal Crystal Geometry
نویسندگان
چکیده
منابع مشابه
Poly(lactic-co-glycolic acid) bone scaffolds with inverted colloidal crystal geometry.
Controllability of scaffold architecture is essential to meet specific criteria for bone tissue engineering implants, including adequate porosity, interconnectivity, and mechanical properties to promote bone growth. Many current scaffold manufacturing techniques induce random porosity in bulk materials, requiring high porosities (>95%) to guarantee complete interconnectivity, but the high poros...
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Bone marrow mesenchymal stem cells (MSCs) are promising candidates for cell therapy and tissue engineering. We used mesenchymal stem cells from human bone marrow (hMSCs) as the seeding cells to investigate the potential of hepatocytic differentiation of hMSCs in porous polylactic glycolic acid (PLGA) scaffolds under perfusion induction. hMSCs were seeded and proliferated in PLGA scaffolds, and ...
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BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...
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Three-dimensional (3D) geometry actively regulates the growth of cells, communication among cells, and interactions between cells and the matrix, as well as cell differentiation pathways. Until now various methods have been utilized to generate a 3D synthetic scaffold, but rarely uniform and ordered structure could be achieved, though it has great advantages. In the course of our study, a new t...
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A novel approach which had foreground of industrialization, surface liquid spraying, was studied in this paper to prepare biodegradable polylactic-co-glycolic acid (PLGA) microspheres for controlled release drug delivery system. To compare with the normal methods, the microspheres prepared by this approach were characterized by particle size distribution and photograph of microscope. The relati...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2008
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2007.0142